A cargo plane has crashed near an airport in Kentucky.
Louisville Metro Police Department (LMPD) say officers are attending the scene of the accident near Louisville International Airport.
The force added: "LMPD and multiple other agencies are responding to reports of a plane crash near Fern Valley and Grade Lane.
"Grade Lane will be closed indefinitely between Stooges and Crittenden. Injuries reported."
UPS said it has been notified of an incident involving one of its aircraft. In a statement on its website, the company said three people were on board.
A shelter-in-place order was also issued within five miles of the Kentucky airport, which is also home to UPS Worldport, the delivery firm's largest package handling facility in the world.
The US Federal Aviation Authority (FAA) said the crash happened around 5.15pm local time (10.15pm UK time) as the plane left the airport, bound for Honolulu in Hawaii.
It added that the aircraft was a McDonnell Douglas MD-11 plane, primarily used by cargo airlines.
Kentucky governor Andy Beshear added on social media: "First responders are onsite, and we will share more information as available.
"Please pray for the pilots, crew and everyone affected. We will share more soon."
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